• Introduction Histone is the core component of chromatin

  2022-01-03

  

  Introduction Histone is the core component of chromatin and histone modification is one of the key mechanisms of epigenetic regulation (Bannister and Kouzarides, 2011). Amino Famprofazone residues on histone tails can be modified under different mechanisms including acetylation, methylation, phosp

• FoxM a downstream target of

  2022-01-03

  

  FoxM1, a downstream target of Gli, has been mainly related to Merimepodib regulation and cellular proliferation in tumor (Alvarez-Fernandez and Medema, 2013, Halasi and Gartel, 2013, Teh et al., 2002). Especially, FoxM1 is a regulator of G1/S and G2/M transitions and M-phase progression (Wonsey & F

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