• Our present data show that neuroleptics can

  2019-07-01

  

  Our present data show that neuroleptics can affect CYP3A via a direct interaction with the enzyme and a significant indirect mechanism (enzyme regulation) produced in vivo. The obtained results revealed interactions of the neuroleptics (added in vitro to control liver microsomes, Model I) with rat C

• Another significant finding in our study was

  2019-07-01

  

  Another significant finding in our study was the demonstration that the axon-protective action associated with CK2 inhibition correlated with preservation of mitochondrial structure and function in Dibutyryl-cAMP, sodium salt (Fig. 11). Because of the consistent protection conferred by CK2 inhibitio

• br Introduction Myotonic dystrophy dystrophia

  2019-07-01

  

  Introduction Myotonic dystrophy (dystrophia myotonica, DM) is an autosomal dominant disorder and the most common form of inherited muscular dystrophy in adults [1]. DM is characterised by a wide range of symptoms, including myotonia, progressive muscle loss, cataracts, cardiac conduction defects,

• The Fontan circulation When first described in the

  2019-07-01

  

  The Fontan circulation When first described in 1971, the Fontan operation ushered in a new paradigm in the care of children born with the varied forms of complex congenital leukotriene receptor antagonist disease (CHD) characterized by a single effective pumping chamber.1., 2. This procedure, whic

• br Grant support This work was supported by

  2019-07-01

  

  Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20

• br Descripci n de las variantes Las variantes

  2019-07-01

  

  Descripción de las variantes Las variantes en los dos poemas estudiados a veces son leves: puntuación, acentuación o actualización de la ortografía. Pero cuando las acotaciones implican cambio de léxico o la sustitución de una parte o de un verso completo, constituyen un problema textual que ayud

• Devemos destacar tamb m o que entendemos

  2019-07-01

  

  Devemos destacar também o que entendemos por Intelectuais, ten-do como suporte para Alisol A what construção do conceito os autores Carlos Altamirano e Jean-François Sirinelli. O termo intelectual, de acordo com Sirinelli, traz em si duas acepções de natureza sociocultural, sendo uma mais ampla, mar

• An anteroposterior AP radiograph of

  2019-06-29

  

  An anteroposterior (AP) radiograph of the pelvis and lateral radiograph of the right hip demonstrated moderate degenerative changes of both hips (Figs. 1 and 2). A provisional differential diagnosis of early avascular necrosis (AVN) or femoroacetabular impingement (FAI) was made. Renal function and

• Lopinavir br Conclusion br Funding br Conflict

  2019-06-29

  

  Conclusion Funding Conflict of interest Acknowledgments Introduction Ventricular tachyarrhythmias (VTs) are life-threatening events that result in hemodynamic compromise; therefore, patients often require immediate treatment such as electrical cardioversion. Despite appropriate manage

• br Conflict of interest br Authors

  2019-06-29

  

  Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in

• Capsaicin weight La estructura del libro apuesta por plantea

  2019-06-29

  

  La estructura del libro apuesta por plantear problemas, pero no por una solución única. De ahí que el desenlace de los capítulos previos sean dos re-flexiones distintas, pero complementarias: por un lado, la precaria fijación textual de un texto “condenado Capsaicin weight existir en una forma que m

• Estas ideas permanecieron vigentes durante mucho tiempo ante

  2019-06-29

  

  Estas ideas permanecieron vigentes durante mucho tiempo antes de la revolución científica desatada por el racionalismo. Un ejemplo es cómo las nociones neumáticas —derivadas de la idea de que el mundo fue creado por un soplo divino— todavía son palpables en el Primero sueño de sor Juana cuando inici

• Bernardo Ar valo de Le n se ala que en

  2019-06-29

  

  Bernardo Arévalo de León señala que en Guatemala la dsn no alcanzó el nivel de desarrollo conceptual que tuvo en otros países como Chile, Brasil y Argentina. Del mismo modo, el general Héctor Alejandro Gramajo Morales, un teórico de la dsn en Guatemala, indicó que si bien el concepto de seguridad n

• SR3335 br Results We evaluated MM patients women and men

  2019-06-29

  

  Results We evaluated 148 MM patients, 87 women and 61 men, age range 29–69 years, 58 of whom developed bacteremia during the early post-transplant period (Table 1). The genotypes were in Hardy–Weinberg equilibrium. We did not observe any statistically significant association between the genotypes

• Teriflunomide br China experienced unprecedented heavy smog

  2019-06-29

  

  China experienced unprecedented heavy smog pollution in the winter of 2016–17. Northern Chinese areas surrounding Beijing suffered most seriously. At the beginning of 2017, the Ministry of Science and Technology of China started to implement a special focus research programme on the causes and con

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