• We are delighted to introduce you to

  2019-05-08

  

  We are delighted to introduce you to the inaugural issue of , a journal that will join and to provide a third pillar in an open-access programme covering the interplay between health and the determinants of health in our living and physical world. What is planetary health? And what kind of scienc

• One study reported the role of

  2019-05-08

  

  One study reported the role of the Purkinje system with respect to the relationship between the septum and HCM-related VT. Santangeli et al. reported that patients with HCM also often have His-Purkinje conduction-related septal abnormalities, and bundle branch block often develops as part of the nat

• After exclusion of secondary causes of eosinophilia diagnost

  2019-05-08

  

  After exclusion of secondary causes of eosinophilia, diagnostic evaluation of primary eosinophilias relies on a combination of morphologic review of the blood and marrow, standard cytogenetics, fluorescent in situ hybridization, flow immunocytometry, and T-cell clonality assessment to detect histopa

• NSC74859 cost br Conclusions and future perspectives br Conf

  2019-05-07

  

  Conclusions and future perspectives Conflict of interest Author’s contributions Introduction Sulfotransferase (SULT)-mediated sulfation and steroid sulfatase (STS)-mediated desulfation represent two opposing mechanisms involved in regulating the chemical and functional homeostasis of end

• dapt secretase It is in this context that

  2019-05-07

  

  It is in this context, that the recent study of Matsuyama et al. sheds further light on the relationships between histoanatomy and atrial arrhythmogenesis . This investigation used high-density optical mapping to study atrial flutter/atrial fibrillation in isolated rat hearts . Atrial arrhythmia was

• De esta forma siguiendo la multicitada met fora

  2019-05-07

  

  De esta forma, siguiendo la multicitada metáfora de Hemingway, el relato policiaco es solamente la punta del iceberg, mientras que los excesos de la política se encuentran debajo del mar (de lama). El relato policíaco, entonces, no es sólo un “pretexto narrativo”, o una simple guía para el lector me

• The patient received multiagent chemotherapy using

  2019-05-07

  

  The patient received multiagent chemotherapy using cyclophosphamide, daunorubicin, vincristine, predonisolone and l-asparaginase, and high dose MTX/Ara-C, as well as the single-agent administration of nelarabine, hydroxyurea and tyrosine kinase inhibitors (TKIs) (imatinib and dasatinib). The convent

• neurotensin receptor br Introduction Homocysteine Hcy is a s

  2019-05-07

  

  Introduction Homocysteine (Hcy) is a sulfur-containing amino neurotensin receptor that has a key role in methionine metabolism. Disturbance of this metabolic pathway may result in the accumulation of Hcy and related abnormal outcomes such as cognitive disorders, cancer, and birth defects. In par

• br Methods The study population comprised

  2019-05-07

  

  Methods The study population comprised 150 patients who underwent implantations of Medtronic dual chamber pacemakers and who had maintained both atrial and ventricular sensing (either in DDD, DDI, or VDD modes) from March 2008 to October 2010. The implanted pterostilbene generators were either Ka

• br Discussion The implant of

  2019-05-07

  

  Discussion The implant of a CRT device in a patient with a resting ejection fraction of 50% represents off-guideline use of this therapy [1]. However, since the patient׳s significant NYHA Class III symptoms, LBBB and exertional ventricular dysfunction achieved evidence-based levels for improvemen

• The congruence between BrS and ERS with respect

  2019-05-07

  

  The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope

• The patient underwent surgery on December A cm elastic lobul

  2019-05-06

  

  The patient underwent surgery on December 2, 2013. A 13 × 13 cm elastic lobulated yellowish tumor, arising from the upper jejunum with suspected local invasion into the transverse colon and mesentery, was detected intraoperatively. Thus, small bowel segmental resection and left hemicolectomy were pe

• RANK RANKL The RANK RANKL signaling

  2019-05-06

  

  RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e

• br Materials methods br Results

  2019-05-06

  

  Materials-methods Results Discussion The general statement that can be concluded from the studies comparing the utility of 18F–NaF PET or PET/CT with 99mTc- MDP whole body bone scintigraphy is that 18F–NaF PET/CT generally has a higher sensitivity and specificity than bone scan. Higher upt

• Introduction The heart beat provides the mechanical

  2019-05-06

  

  Introduction The heart beat provides the mechanical force for the pumping of oxygenated blood to, and deoxygenated blood away from, the peripheral tissues [1]. This depends critically on the orderly activation and recovery of electrical excitation through the myocardium. Disruptions of this can lea

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