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br Discussion Over the past two decades
2019-05-30
Discussion Over the past two decades, the incidence of second primary malignancy has progressively risen among cancer survivors and is an issue of increasingly greater concern in oncology. The increasing incidence may be due to the elevated rate of early cancer detection, improved cancer treatmen
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In summary we have established an
2019-05-30
In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibrom
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br Results As shown in Table
2019-05-30
Results As shown in Table 1, the amplitude, and the onset or the end of LA potentials were successfully determined via visual inspection. Among 19 patients with AP, LA potentials were detected in 7 (37%), all in an LA → CSM activation sequence (Fig. 2). In contrast, among 21 patients with CCW AFL
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En M xico el folclor nacionalista de los
2019-05-30
En México, el folclor nacionalista de los siglos xix y xx matizó la tipificada creencia cultural de la “convivencia natural” del mexicano con la muerte para explicar y sobrellevar, incluso de manera socarrona, los estragos económicos y sociales del destino mexicano. Elsa Malvido, en este sentido, en
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br Role of ICD treatment In patients with VT
2019-05-29
Role of ICD treatment In patients with VT associated with various structural TAE226 diseases, ICD therapy is recommended even if the target VT is successfully ablated and no VT is inducible after catheter ablation [29]. This is because, in such patients, the same VT and/or new VT recurs during t
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Las pol ticas cosmopolitas de Or genes
2019-05-29
Las políticas cosmopolitas de Orígenes, por su parte, combinaron los intereses de sus directores, José Lezama Lima y José Rodríguez Feo. El primero, estaba empeñado en la formación de un grupo poético creativo, que trabajara en el diseño de una teleología para el proyecto republicano. Esta teología
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Real time quantitative polymerase chain reaction RQ
2019-05-29
Real-time quantitative polymerase chain reaction (RQ-PCR) was performed to quantify BCR/ABL1 transcript as described previously [1]. The quantitative results were expressed as percent ratios relative to an ABL1 internal control using the following formula (p210 BCR–ABL/ABL1×100×CF) [2]. The level o
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br Water the main component of Earth s ecosystems
2019-05-29
Water—the main component of Earth\'s ecosystems—concentrates some of the most worrying global concerns that have emerged during the Anthropocene. When it comes to health considered at a planetary level, the challenges related to water can be sorted into five main categories: pollution, access to w
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Although preoperative rehabilitation may have a strong
2019-05-29
Although preoperative rehabilitation may have a strong impact on survival if additional patients are qualified for curative resection, yet strong evidence remains lacking to support the regimens for patients who have lung cancer. This may be due to, in part, the relatively brief g protein coupled re
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br Introduction Despite the widespread use of
2019-05-29
Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested
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br Erythropoietin and the HSC niche Many molecules
2019-05-29
Erythropoietin and the HSC niche Many molecules produced both locally and systemically, including erythropoietin (Epo) and adrenergic catecholamines, also appear to affect HSC niche and metastatic lesions in the bone marrow. EPO is a hematopoietic hormone produced predominantly in the kidneys in
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Furthermore permanent cardiac pacemaker implantation may be
2019-05-29
Furthermore, permanent cardiac pacemaker implantation may be required when severe bradyarrhythmia recurs for a long period. Sympathetic preganglionic neurons innervating the cgrp may be damaged beyond recovery in such cases [2]. Since placement of new leads immediately after infected lead removal ha
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LQTS is classified into subtypes LQT to LQT based
2019-05-29
LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ
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To date over mutations in KCNQ have been
2019-05-29
To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [
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purchase thapsigargin Cryotherapy related soft tissue injury
2019-05-28
Cryotherapy related soft tissue injury usually occurs within a few weeks postoperatively. Skin necrosis is a significant complication if freezing of the superficial surface occurs. Constant irrigation of the adjacent tissues with warm saline reduces the chance of skin necrosis. Our rate of infection
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